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839 Health Sciences Rd, Sprague Hall
Irvine, CA 92697


The Angela Fleischman lab at UC Irvine is dedicated to understanding the pathogenesis of myeloproliferative neoplasms  (MPN or MPD) which includes polycythemia vera, essential thrombocythemia, myelofibrosis). Our focus is on the role of inflammation in MPN.




Come hear about our work at ASH 2014

Sarah Morse

 The Annual Meeting for the American Society of Hematology (ASH) is rapidly approaching! Come see us in San Francisco this weekend to hear more about our research. We have three poster presentations spanning Saturday through Monday in section 635, sessions I, II, and III.

First, Dr. Fleischman will be discussing T cell-mediated suppression of hematopoiesis in MPN Saturday evening. On Sunday, graduate student Stefan Brooks will be presenting our findings that expression of Jak2V617I does not result in overt MPN, but does result in cytokine hypersensitivity. Finally, research assistant Betty Lai will discuss her work showing that an exaggerated response to toll-like receptor agonist contributes to excessive TNF production in MPN on Monday.

We look forward to seeing you there! If you aren't able to attend, please see the links above to find out more about each of our projects, as well as other MPN research being presented at ASH 2014.